Bitkisel Nutrasötiklerdeki Antineoplastik Etkilerin Sitolojik ve Nutrisyonel Genomik Yaklaşımlarla Değerlendirilmesi

This book, "Bitkisel Nutrasötiklerdeki Antineoplastik Etkilerin Sitolojik ve Nutrisyonel Genomik Yaklaşımlarla Değerlendirilmesi" ("Evaluation of Antineoplastic Effects of Herbal Nutraceuticals with Cytological and Nutritional Genomic Approaches"), investigates the potential of herbal nutraceuticals in the fight against cancer, a critical global health problem. Edited by Assist. Prof. Dr. Emine Sacide ÇAĞLAYAN AYDOĞAN, this work, developed from projects by graduate students of Nutritional and Dietetics, focuses on evaluating the antineoplastic (anti-cancer) effects of food components using clinical, cytological, and nutritional genomic (nutrient-gene interaction) methods. The book's main themes include cell death mechanisms (apoptosis, autophagy), the relationship between the immune system and metastasis, the role of the mTOR signaling pathway in cancer, and alternative or complementary approaches to conventional cancer therapies (chemotherapy, radiotherapy, immunotherapy). It examines the bioactive components of plants like jujube (Ziziphus Jujuba) and milk thistle (Silybum marianum)—such as triterpenic acids, silymarin, vitexin, and ferulic acid—demonstrating their antiproliferative and apoptotic mechanisms on various cancer cell lines. This publication serves as a guide for young scientists researching nutritional strategies, particularly the efficacy and safety of high-dose nutraceutical use, in cancer prevention and therapyz"Evaluation of Antineoplastic Effects of Herbal Nutraceuticals with Cytological and Nutritional Genomic Approaches," investigates the potential of herbal nutraceuticals in the fight against cancer, a critical global health problem. Edited by Assist. Prof. Dr. Emine Sacide ÇAĞLAYAN AYDOĞAN, this work, developed from projects by graduate students of Nutritional and Dietetics, focuses on evaluating the antineoplastic (anti-cancer) effects of food components using clinical, cytological, and nutritional genomic (nutrient-gene interaction) methods. The book's main themes include cell death mechanisms (apoptosis, autophagy), the relationship between the immune system and metastasis, the role of the mTOR signaling pathway in cancer, and alternative or complementary approaches to conventional cancer therapies (chemotherapy, radiotherapy, immunotherapy). It examines the bioactive components of plants like jujube (Ziziphus Jujuba) and milk thistle (Silybum marianum)—such as triterpenic acids, silymarin, vitexin, and ferulic acid—demonstrating their antiproliferative and apoptotic mechanisms on various cancer cell lines. This publication serves as a guide for young scientists researching nutritional strategies, particularly the efficacy and safety of high-dose nutraceutical use, in cancer prevention and therapy.